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Updated: Aug 16, 2026

Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta
Published on: April 3, 2017
Separation of the umbilical cord--histological findings
A M Oudesluys-Murphy1, J C den Hollander
1Department of Paediatrics, Zuiderziekenhuis, Rotterdam, The Netherlands.
Abstract:
Even though the separation of the umbilical cord receives a great deal of interest, the process of cord separation has not been reported in the literature. A histological study of the umbilical area was carried out on 25 neonates who died within 7 days of birth (mean age at death 3 days). The umbilical cord itself became dried and mummified. Polymorphonuclear leucocytes infiltrated the areas between the mummifying cord stump and the vital tissues of the abdominal wall, forming a demarcation zone. No other leucocytes were present, and no bacteria were seen in any of the preparations studied.
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