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Related Experiment Video

Updated: May 9, 2026

Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis

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Interview with Lisa Shipley. Interviewed by Lisa Parks.

|August 3, 2013

Summary

Lisa Shipley leads preclinical and clinical ADME activities and biomarker assay development at Merck. Her extensive experience spans drug disposition, pharmacokinetics, and pharmacodynamics from discovery to post-launch.

Area of Science:

Pharmacology and Toxicology
Drug Metabolism
Bioanalysis

Background:

Lisa Shipley holds a doctoral degree in Pharmacology and Toxicology.
She has over 20 years of experience at Eli Lilly and Company.
Shipley has held leadership roles in Lean Six Sigma and Drug Disposition, PK/PD, and Trial Simulations.

Discussion:

Shipley is responsible for preclinical and clinical ADME (Absorption, Distribution, Metabolism, Excretion) activities.
She oversees molecular biomarker assay development at Merck Research Laboratories.
Her role supports programs from discovery through post-product launch.

Key Insights:

Expertise in pharmacokinetics, pharmacodynamics, and drug metabolism is crucial for drug development.
Effective management of ADME activities and biomarker assays ensures successful program progression.

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A strong foundation in pharmacology and toxicology informs strategic decision-making.

Outlook:

Continued advancements in ADME and biomarker strategies will accelerate drug development timelines.
Cross-functional leadership in drug disposition and PK/PD is essential for optimizing clinical trial simulations.
The integration of molecular biomarker assays enhances precision medicine approaches.