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Updated: May 9, 2026

Mechanical Stimulation-induced Calcium Wave Propagation in Cell Monolayers: The Example of Bovine Corneal Endothelial Cells
Published on: July 16, 2013
Calcium waves with mechano-chemical couplings
Bogdan Kazmierczak1, Zbigniew Peradzynski
1Institute of Fundamental Technological Research, Polish Academy of Sciences, Pawinskiego 5B, 02-106 Warsaw, Poland. bkazmier@ippt.gov.pl
Abstract:
As follows from experiments, waves of calcium concentration in biological tissues can be easily excited by a local mechanical stimulation. Therefore the complete theory of calcium waves should also take into account coupling between mechanical and chemical processes. In this paper we consider the existence of travelling waves for buffered systems, as in [22], completed, however, by an equation for mechanical equilibrium and respective mechanochemical coupling terms. Thus the considered, coupled system consists of reaction-diffusion equations (for the calcium and buffers concentrations) and equations for the balance of mechanical forces.
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