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Hemoglobin Jerez [α2 β2 95 (FG2) Lys→Gln]: performance of HbA1c measurement with five analytical methods

María L González-Borrachero1, Paloma Ropero-Gradilla, José M Vergara-Chozas

  • 1Servicio de Análisis Clínicos, Hospital Universitario de Jerez, Carretera de Circunvalación, s/n., 11407 Jerez de la Frontera, Spain.

Clinica Chimica Acta; International Journal of Clinical Chemistry
|August 3, 2013
PubMed
Abstract

No abstract available in PubMed .

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Hemoglobin01:24

Hemoglobin

Hemoglobin is a globular protein made up of four subunits. Two of these subunits are alpha chains, and the other two are beta chains. Each subunit contains a molecule of heme, which has an iron atom and can bind to oxygen. When an oxygen molecule binds to one heme group, it changes the shape of hemoglobin, making it easier for the other heme groups to bind oxygen as well.
When all four heme groups are bound to oxygen, the resulting molecule is called oxyhemoglobin. As a result, arterial blood...