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Updated: May 9, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
08:51

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

Comorbidities at multiple sclerosis diagnosis.

Agnès Fromont1, Christine Binquet, Fabien Rollot

  • 1Department of Neurology, University Hospital of Dijon, 3 rue du Faubourg Raines, 21000, Dijon, France.

Journal of Neurology
|August 3, 2013
PubMed
Summary
This summary is machine-generated.

Comorbidities at multiple sclerosis (MS) diagnosis are uncommon, with psychiatric disorders and diabetes being more frequent in MS patients. Patients with comorbidities were diagnosed with MS later in life.

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Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
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Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

Area of Science:

  • Neurology
  • Epidemiology
  • Public Health

Background:

  • Multiple sclerosis (MS) is a chronic neurological disease with significant healthcare implications.
  • Understanding comorbidities in MS is crucial for comprehensive patient management.
  • In France, MS is recognized as a long-term illness (ALD) with full cost coverage.

Purpose of the Study:

  • To determine the nature and frequency of comorbidities at the time of multiple sclerosis (MS) diagnosis.
  • To compare the age of MS diagnosis in patients with and without comorbidities.

Main Methods:

  • A retrospective study analyzed 22,087 patients diagnosed with MS before age 45 between 1995 and 2004 in France.
  • Comorbidities diagnosed concurrently with MS were identified and categorized.
  • Age at MS diagnosis was compared between patients with and without pre-existing conditions.

Main Results:

  • Only 3% of MS patients had a diagnosed comorbidity at the time of MS notification.
  • The most common comorbidities included psychiatric (40.2%), autoimmune (24.5%), cardiovascular (16.2%), cancer (12.2%), and metabolic (9.0%) diseases.
  • Patients with comorbidities were diagnosed with MS at a later average age (36.9 years) compared to those without (33.6 years).
  • Psychiatric disorders and diabetes were observed more frequently in MS patients than in the general population.

Conclusions:

  • Comorbidities at the time of multiple sclerosis diagnosis are infrequent.
  • Psychiatric disorders and diabetes represent significant comorbidities in the MS population.
  • The presence of comorbidities is associated with a delayed diagnosis of MS.