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Related Experiment Video

Updated: May 9, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
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Published on: May 26, 2023

Sturge-weber syndrome.

Catherine D Bachur1, Anne M Comi

  • 1Neurology and Developmental Medicine, Hugo W. Moser Research Institute at Kennedy Krieger, 801 N. Broadway, Room 553, Baltimore, MD, 21205, USA, comi@kennedykrieger.org.

Current Treatment Options in Neurology
|August 3, 2013
PubMed
Summary

Early intervention for babies with suspected Sturge-Weber syndrome (SWS) involves anticipatory guidance for seizures and ophthalmology referrals. Presymptomatic diagnosis guides treatment with aspirin and anticonvulsants like levetiracetam for better seizure control.

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Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
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Published on: September 19, 2019

Area of Science:

  • Neurology
  • Pediatrics
  • Genetics

Background:

  • Sturge-Weber syndrome (SWS) is a rare congenital disorder.
  • Early detection and intervention are crucial for managing SWS symptoms, particularly seizures and brain involvement.
  • Understanding the genetic basis, specifically somatic mutations, is advancing treatment strategies.

Purpose of the Study:

  • To outline a proactive approach for managing infants at risk for SWS.
  • To detail diagnostic methods and treatment protocols for presymptomatic and symptomatic SWS.
  • To discuss surgical and medical management options for refractory seizures in SWS.

Main Methods:

  • Clinical assessment including history, physical examination, and electroencephalogram (EEG).
  • Magnetic resonance imaging (MRI) with contrast for diagnosing brain involvement.
  • Pharmacological interventions including low-dose aspirin and anticonvulsants (levetiracetam, oxcarbazepine).

Main Results:

  • Aggressive seizure management with combination therapy aims for complete suppression.
  • Surgical intervention is considered for medically refractory seizures in select unilateral cases.
  • Ketogenic diet and vagal nerve stimulation are alternative therapies with variable success.

Conclusions:

  • A multidisciplinary approach is essential for optimal SWS management.
  • Timely diagnosis and treatment can improve seizure control and developmental outcomes.
  • Ongoing research into the genetic underpinnings of SWS offers hope for novel therapeutics.