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Morphological studies of bradykinin-treatments on the rat trigeminal sensory neuron
C Kudoh1, K Inomata, R G Calderhead
1Department of Anatomy, Toho University School of Medicine, Tokyo, Japan.
Journal of Submicroscopic Cytology and Pathology
|July 1, 1990
Abstract:
Subcutaneous injections of bradykinin to the rat trigeminal region over 4 days produced a significant increase in the number of mitochondria in the small trigeminal ganglion cells and the central terminals of unmyelinated fibers in the spinal trigeminal nucleus. In the large trigeminal ganglion cells, no significant change in the number of mitochondria was observed. These results seem to demonstrate that bradykinin stimulates unmyelinated nerve and increases its energy consumption.