[Studies on the microcirculatory architecture in five colonic neoplasms]

The microcirculatory architecture of colonic neoplasms was prepared with methylmethacrylate cast. Scanning electron microscopy showed that microcirculation was deficient in the central area of neoplasms, but increased markedly and become claw, sinus and sphere patterns in appearance at the periphery of neoplasms. The microcirculation of the transitional mucosa lost its typical hexagon structure, becoming larger in diameter and showing increase of branches. These results suggest that the technique described in this article can be used to show the morphologic changes of neoplastic microcirculation, which may be worthy for the future investigation of neoplasm development.