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Related Concept Videos

Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...

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Related Experiment Video

Updated: May 9, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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Unusual choroidal mass.

Swapnil Madhukar Parchand1, Kusum Sharma, Aman Sharma

  • 1Advanced Eye Centre, Department of Ophthalmology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

BMJ Case Reports
|August 3, 2013
PubMed
Summary
This summary is machine-generated.

Disseminated tuberculosis mimicked ovarian cancer in a young woman, presenting solely as an eye choroidal mass. Early diagnosis using molecular tests confirmed tuberculosis, leading to effective treatment.

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Oncology

Background:

  • Disseminated tuberculosis (TB) can present with diverse clinical manifestations.
  • Ocular involvement in TB is uncommon and can mimic other pathologies.

Observation:

  • A 19-year-old female presented with a choroidal mass, initially suspected as metastasis.
  • Systemic evaluation revealed lymphadenopathy, elevated CA-125, and imaging suggestive of ovarian malignancy.
  • Ocular and ascitic fluid analysis showed granulomatous inflammation but negative acid-fast bacilli stains.

Findings:

  • Multiplex PCR on ascitic fluid confirmed Mycobacterium tuberculosis using MPB64 and IS6110 sequences.
  • The patient was diagnosed with disseminated tuberculosis masquerading as choroidal metastasis.
  • Treatment with antitubercular therapy resulted in a positive clinical response.

Implications:

  • This case highlights the importance of considering tuberculosis in the differential diagnosis of choroidal masses, even without typical inflammatory signs.
  • Advanced molecular diagnostic techniques are crucial for identifying atypical presentations of disseminated TB.
  • Timely diagnosis and treatment are essential for favorable outcomes in disseminated tuberculosis.