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Nail involvement in osteoarthritis.

M Cutolo1, M A Cimmino, S Accardo

  • 1Istituto Scientifico di Medicina Interna, Universita' di Genova, Italy.

Clinical Rheumatology
|June 1, 1990
PubMed
Summary
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Osteoarthritis of the hand can cause nail changes like leukonychia and ridges. Treatments targeting inflammation of osteoarthritic nodes improved these nail conditions.

Area of Science:

  • Rheumatology
  • Dermatology
  • Orthopedics

Background:

  • Primary interphalangeal osteoarthritis of the hand is common.
  • Nail involvement is an underreported manifestation of hand osteoarthritis.
  • Heberden's nodes, characteristic of osteoarthritis, may influence nail changes.

Observation:

  • Two cases of hand osteoarthritis with associated nail abnormalities are presented.
  • Observed nail changes included leukonychia (nail whitening) and longitudinal nail ridges.
  • These nail lesions were linked to osteoarthritic changes in the distal interphalangeal joints.

Findings:

  • Direct pressure from osteoarthritic joints on the nail matrix can cause nail lesions.
  • Compromised local blood flow due to osteoarthritis may contribute to nail alterations.

Related Experiment Videos

  • Inflammation of Heberden's nodes appears to play a role in developing nail changes.

    • Implications:

    • Leukonychia resolved following local steroidal anti-inflammatory treatment of osteoarthritic nodes.
    • Longitudinal nail ridges resolved after treatment with nonsteroidal anti-inflammatory agents.
    • These findings suggest a link between hand osteoarthritis and nail pathology, treatable with anti-inflammatory therapies.