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Related Concept Videos

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Factors Influencing Heart Rate

The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
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Physiological Foundation of Stress

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Related Experiment Video

Updated: May 9, 2026

Autonomic Function Following Concussion in Youth Athletes: An Exploration of Heart Rate Variability Using 24-hour Recording Methodology
05:48

Autonomic Function Following Concussion in Youth Athletes: An Exploration of Heart Rate Variability Using 24-hour Recording Methodology

Published on: September 21, 2018

Do physiological and pathological stresses produce different changes in heart rate variability?

Andrea Bravi1, Geoffrey Green, Christophe Herry

  • 1Department of Cellular and Molecular Medicine, University of Ottawa Ottawa, ON, Canada ; Ottawa Hospital Research Institute Ottawa, ON, Canada.

Frontiers in Physiology
|August 3, 2013
PubMed
Summary

Both physiological exercise and pathological infection reduce heart rate variability (HRV). However, distinct patterns of HRV alteration emerge depending on the stressor, particularly in sympathovagal modulation.

Keywords:
dimensions of variabilitydiseasedomains of variabilityexercisephysical activitysepsis

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Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions
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Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions

Published on: June 5, 2019

Related Experiment Videos

Last Updated: May 9, 2026

Autonomic Function Following Concussion in Youth Athletes: An Exploration of Heart Rate Variability Using 24-hour Recording Methodology
05:48

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Published on: September 21, 2018

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions
08:12

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions

Published on: June 5, 2019

Area of Science:

  • Cardiovascular Physiology
  • Stress Response
  • Data Analysis

Background:

  • Physiological and pathological stressors impact cardiovascular system function.
  • Reduced heart rate variability (HRV) is a known consequence of various stressors.
  • The specific patterns of HRV alteration across different stress types require further elucidation.

Purpose of the Study:

  • To investigate whether the reduction in HRV during physiological (exercise) and pathological (sepsis) stress follows similar patterns.
  • To compare HRV changes across different variability domains in response to distinct stressors.
  • To explore differences in HRV interrelationships during exercise versus sepsis.

Main Methods:

  • Utilized Continuous Individualized Multiorgan Variability Analysis (CIMVA™) software for windowed analysis of heart rate (HR) and HRV.
  • Compared HRV data from healthy subjects during exercise with data from bone marrow transplant patients who developed sepsis.
  • Employed Wilcoxon sign-rank test to compare baseline and stress-induced HRV levels.

Main Results:

  • Both exercise and sepsis induced similar trends in HR and four selected HRV measures.
  • The low frequency/high frequency (LF/HF) ratio, indicative of sympathovagal modulation, was altered by exercise but not by sepsis.
  • HRV measures exhibited lower inter-correlation during sepsis compared to exercise.

Conclusions:

  • Cardiovascular responses to exercise and sepsis share similarities but exhibit distinct patterns.
  • Differences in HRV correlation and inter-subject variability during sepsis warrant further investigation.
  • This study provides insights into the nuanced cardiovascular adaptations to diverse stressors.