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Related Concept Videos

What is Genetic Engineering?00:49

What is Genetic Engineering?

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CRISPR01:59

CRISPR

Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced Short...
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Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
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Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
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Mouse Genome Engineering Using Designer Nucleases
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Genetic technologies and ethics.

Ali M Ardekani1

  • 1Reproductive Biotechnology Research Center.

Journal of Medical Ethics and History of Medicine
|August 3, 2013
PubMed
Summary
This summary is machine-generated.

The complete human genome sequence offers significant benefits for disease diagnosis and treatment. However, genetic technologies also present complex ethical, legal, and social challenges requiring societal attention.

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Area of Science:

  • Genomics
  • Bioethics
  • Social Sciences

Background:

  • The human genome has been fully sequenced, profoundly impacting biological and social sciences.
  • Identification of approximately 25,000 human genes promises advancements in disease diagnosis and treatment.

Purpose of the Study:

  • To highlight the dual nature of genetic technologies, encompassing both potential benefits and ethical challenges.
  • To emphasize the need for societal leaders to address the ethical, legal, and social implications of genetic advancements.

Main Methods:

  • Review of current knowledge in genomics and genetic technologies.
  • Analysis of ethical, legal, and social issues arising from genetic applications.
  • Discussion of societal preparedness for genetic technology advancements.

Main Results:

  • Genetic technologies offer substantial potential for improving human health and well-being.
  • Significant ethical dilemmas have emerged concerning stem cells, cloning, gene therapy, and genetic selection.
  • The transformative power of these technologies necessitates proactive societal engagement.

Conclusions:

  • Societal leaders must actively engage with the ethical, legal, and social dimensions of genetic technologies.
  • Preparedness is crucial to navigate the challenges and harness the benefits of genetic advancements for the future.
  • The ongoing evolution of genetic science demands continuous dialogue and policy development.