Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Gastroesophageal reflux disease. Standards of the Czech Society of Gastroenterology--actualization 2009].

Vnitrni lekarstvi·2009
Same author

[Lower dyspeptic syndrome. Recommended diagnostic and therapeutic procedures for general practitioners 2006].

Casopis lekaru ceskych·2007
Same author

[Incidence of hiatal hernias in the current endoscopic praxis].

Casopis lekaru ceskych·2007
Same author

[Hereditary forms of colorectal adenomatous polyposis].

Casopis lekaru ceskych·2006
Same author

[Diagnosis of familial adenomatous polyposis].

Vnitrni lekarstvi·2002
Same author

Phenotype of cytochrome P450 CYP2D6 in patients with familial adenomatous polyposis.

Methods and findings in experimental and clinical pharmacology·2001

Related Experiment Video

Updated: May 9, 2026

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
04:09

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors

Published on: February 13, 2026

[Digestive tract polyposes].

V Jirásek1

  • 1IV. interní klinika 1. lékařské fakulty UK a VFVN Praha. jirasek.vacl@seznam.cz

Vnitrni Lekarstvi
|August 6, 2013
PubMed
Summary
This summary is machine-generated.

Hereditary polyposis syndromes affect the digestive tract due to genetic factors. Management involves diagnosis and either operative or endoscopic therapy for these conditions.

More Related Videos

Postoperative Ileus Murine Model
04:26

Postoperative Ileus Murine Model

Published on: July 12, 2024

Related Experiment Videos

Last Updated: May 9, 2026

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
04:09

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors

Published on: February 13, 2026

Postoperative Ileus Murine Model
04:26

Postoperative Ileus Murine Model

Published on: July 12, 2024

Area of Science:

  • Gastroenterology
  • Genetics
  • Oncology

Background:

  • Hereditary polyposis syndromes are genetic conditions impacting the digestive tract.
  • These syndromes involve the development of numerous polyps, increasing cancer risk.
  • Understanding their genetic basis is crucial for diagnosis and management.

Purpose of the Study:

  • To provide a comprehensive overview of hereditary polyposis syndromes.
  • To detail the underlying genetic mechanisms.
  • To summarize symptoms, diagnostic procedures, and therapeutic options.

Main Methods:

  • Literature review of hereditary polyposis syndromes.
  • Analysis of genetic mechanisms.
  • Summary of clinical presentation and management strategies.

Main Results:

  • Detailed explanation of genetic factors in polyposis.
  • Inclusion of extragastrointestinal signs and symptoms.
  • Listing of key diagnostic procedures.
  • Overview of operative and endoscopic treatment modalities.

Conclusions:

  • Hereditary polyposis syndromes require thorough genetic understanding.
  • Early diagnosis and appropriate management, including operative or endoscopic interventions, are vital.
  • Further research into genetic mechanisms can improve patient outcomes.