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Related Experiment Videos

Transition from nutcracker esophagus to achalasia.

A Anggiansah1, N F Bright, M McCullagh

  • 1Department of Surgery, Guy's Hospital, London, U.K.

Digestive Diseases and Sciences
|September 1, 1990
PubMed
Summary

Nutcracker esophagus, a condition of esophageal spasms, can transform into achalasia of the cardia over time. This case study documents the first reported instance of this progression, highlighting the importance of long-term patient monitoring.

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Erratum.

Planta·2013

Area of Science:

  • Gastroenterology
  • Esophageal Motility Disorders
  • Clinical Case Studies

Background:

  • Nutcracker esophagus is a manometric diagnosis defined by high-amplitude, prolonged esophageal peristaltic contractions.
  • Its association with dysphagia and chest pain is well-documented in esophageal motility research.
  • Long-term natural history studies of nutcracker esophagus are scarce.

Observation:

  • A patient initially diagnosed with nutcracker esophagus presented with dysphagia.
  • Follow-up investigations three years later revealed the development of achalasia of the cardia.
  • This represents a significant progression of esophageal motility dysfunction.

Findings:

  • The study reports the first documented case of nutcracker esophagus transitioning to achalasia.

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  • This progression challenges the understanding of the natural history of esophageal motility disorders.
  • High-amplitude, prolonged peristaltic contractions may evolve into a loss of esophageal peristalsis and lower esophageal sphincter dysfunction.

    • Implications:

    • This finding suggests a potential continuum between different esophageal motility disorders.
    • Clinicians should consider the possibility of progression in patients diagnosed with nutcracker esophagus.
    • Further research into the mechanisms driving this transition is warranted to improve patient management and treatment strategies.