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Control of size in losartan/copper(II) coordination complex hydrophobic precipitate

Ângelo M L Denadai1, Jeferson G Da Silva, Pedro P G Guimarães

  • 1Departamento de Farmácia, Universidade Federal de Juiz de Fora (UFJF), Campus Governador Valadares, Av. Dr. Raimundo Monteiro de Rezende, 330, Centro, 35010-177 Governador Valadares, MG, Brazil. angelomld@gmail.com

Materials Science & Engineering. C, Materials for Biological Applications
|August 6, 2013
PubMed

Keywords:
CRSControl of sizeCoordination complexCopperD(h)DLSDSCEPRHPHydrophobic precipitateITCKLosLosLos(−)Los/Cu(II)LosartanRStepwise complexationTGAZP[KLos]/[Cu(OAc)(2)] molar ratiobonded losartancontrolled release systemdifferential scanning calorimetrydynamic light scatteringelectron paramagnetic resonance spectroscopyhydrodynamic diameterhydrophobic precipitateisothermal titration calorimetrylosartan anionlosartan potassiumlosartan/copper coordination complexmolar partial enthalpy of titrantthermodynamic parameter of reactionthermogravimetric analysiszeta potentialΔ(r)X°

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