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Updated: May 9, 2026
Mass Spectrometric Analysis of Glycosphingolipid Antigens
Published on: April 16, 2013
Demonstration of ethyl glucuronide in dental tissue samples by liquid chromatography/electro-spray tandem mass
Cem Zeren1, Alper Keten, Salih Çelik
1Mustafa Kemal University, Medical Faculty, Department of Forensic Medicine, Hatay, Turkey.
Introduction:
Ethyl glucuronide (EtG) has been studied in various tissues and body fluid for determination of alcohol intake. However, no study, dealing with EtG analysis in dental tissue, was performed so far. In this study, we aimed to demonstrate EtG levels in dental tissue.
Materials And Methods:
Michigan Alcohol Screening Test (MAST) was performed to 29 participants. Following the test, cases were divided into three groups as non-hazardous alcohol users, alcohol abusers and 6 controls who verbally declared that they were abstainers. A total of 29 tooth specimens, obtained from participants, was included in the study. These specimens were analyzed using LC/MS/MS.
Results:
All of the participants included in the study were male. According to the MAST outcomes 14 of the participants were non-hazardous alcohol users, and 9 were alcohol abusers, while 6 patients verbally declared that they were abstainers. Dental tissue analyses revealed EtG levels ranging between EtG
Conclusion:
The findings of the present study demonstrated that dental tissue can be used for detection of alcohol intake, using LC/MS/MS.
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