Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Early yaws: a light microscopic study.

H J Engelkens1, V D Vuzevski, J Judanarso

  • 1University Hospital Rotterdam-Dijkzigt, The Netherlands.

Genitourinary Medicine
|August 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Treatment of sugarcane vinasse in AnMBR and UASB: process performance and microbial community comparison.

Frontiers in bioengineering and biotechnology·2024
Same author

Evidence for changes in population-level subjective well-being during the COVID-19 pandemic from 30 waves of representative panel data collected in Austria between March 2020 and March 2022.

Public health·2022
Same author

Trajectories of loneliness, depressive symptoms, and anxiety symptoms during the COVID-19 pandemic in Austria.

Public health·2022
Same author

Longitudinal effects of COVID-19-related loneliness on symptoms of mental distress among older adults in Austria.

Public health·2021
Same author

Pre-treatments to enhance the biodegradability of waste activated sludge: Elucidating the rate limiting step.

Biotechnology advances·2018
Same author

Rheological characterisation of concentrated domestic slurry.

Water research·2018
Same journal

Syndromic management of sexually transmitted diseases in developing countries: what role in the control of the STD and HIV epidemics?

Genitourinary medicine·1998
Same journal

Acceptability of clinics for sexually transmitted diseases among users of the "gay scene" in the West Midlands.

Genitourinary medicine·1998
Same journal

Chronic balanitis: an unusual localisation of necrobiosis lipoidica.

Genitourinary medicine·1998
Same journal

Microsporum canis infection of the penis.

Genitourinary medicine·1998
Same journal

Foreign body granuloma of the penis caused by occupational glass fibre exposure.

Genitourinary medicine·1998
Same journal

Kaposi sarcoma presenting as severe haemoptysis.

Genitourinary medicine·1998
See all related articles

Light microscopy revealed characteristic yaws histopathology in 27 of 45 patients. Treponemes were identified in skin biopsies, confirming early yaws diagnosis in most cases.

Area of Science:

  • Dermatopathology
  • Infectious Diseases
  • Microbiology

Background:

  • Yaws is a neglected tropical infection caused by Treponema pallidum subspecies.
  • Early diagnosis is crucial for effective treatment and prevention of long-term sequelae.
  • Histopathological examination of skin lesions aids in yaws diagnosis.

Purpose of the Study:

  • To describe the light microscopic findings in skin biopsies from patients with suspected early yaws.
  • To correlate histopathological features with the presence of treponemes.
  • To evaluate the utility of light microscopy in diagnosing early yaws.

Main Methods:

  • Light microscopy of skin biopsies from 45 patients with suspected early yaws.
  • Histopathological analysis of epidermal and dermal changes.

Related Experiment Videos

  • Steiner staining for visualization of treponemes.

    • Main Results:

    • Typical yaws histopathology observed in 27 cases (parakeratosis, acanthosis, spongiosis, microabscesses, inflammatory infiltrate).
    • Treponemes identified via Steiner staining in 23 of 27 histopathologically confirmed cases.
    • Seven additional cases were suggestive of yaws; six had alternative diagnoses.

    Conclusions:

    • Light microscopy is valuable for diagnosing early yaws, showing characteristic histopathological features.
    • The presence of treponemes in biopsies confirms the diagnosis.
    • Histopathology aids in differentiating yaws from other skin conditions.