Degradation of human cartilage by monocytes
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L M Kumaratilake1, I C Kowanko, E J Bates
1Department of Immunology, Adelaide Children's Hospital, North Adelaide, South Australia.
Immunology Letters
|July 1, 1990
Abstract:
The effect of human peripheral blood monocytes on the degradation of human articular cartilage was studied in vitro using a radiometric assay to detect proteoglycan breakdown. The results showed that proteoglycan breakdown was increased by 60% after a 20 h exposure to monocytes (p less than 0.001).