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Updated: May 9, 2026

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice

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Published on: October 18, 2024

Metabolic surgery: quo vadis?

Ana M Ramos-Leví¹, Miguel A Rubio Herrera¹

¹Servicio de Endocrinología y Nutrición, Hospital Clínico San Carlos, IdISSC, Madrid, Spain.

Endocrinologia Y Nutricion : Organo De La Sociedad Espanola De Endocrinologia Y Nutricion

|August 6, 2013

Summary

This summary is machine-generated.

Metabolic surgery, including bariatric procedures, shows promise for resolving type 2 diabetes mellitus (T2D). This review critically analyzes T2D remission rates and discusses surgical indications for non-morbidly obese patients.

Keywords:

Bariatric surgery Cirugía bariátrica Cirugía metabólica Diabetes mellitus tipo 2 Metabolic surgery Morbid obesity Obesidad Obesidad mórbida Obesity Remisión de la diabetes mellitus tipo 2 Review Revisión Type 2 diabetes mellitus Type 2 diabetes mellitus remission

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Area of Science:

Endocrinology and Metabolism
Surgical Gastroenterology

Background:

Bariatric surgery is increasingly recognized for its metabolic benefits beyond weight loss.
The term "metabolic surgery" is gaining traction for procedures targeting diseases like type 2 diabetes mellitus (T2D).
Global discussions on metabolic surgery recommendations are ongoing, yet a definitive consensus remains elusive.

Purpose of the Study:

To critically analyze controversies surrounding metabolic surgery for type 2 diabetes mellitus (T2D).
To evaluate T2D remission rates achieved with various bariatric procedures using diverse definition criteria.
To discuss the indications for metabolic surgery in T2D patients who are not morbidly obese.

Main Methods:

Systematic review and critical analysis of existing literature on metabolic surgery and T2D remission.
Comparative analysis of T2D remission rates across different bariatric procedures.
Examination of various criteria used to define diabetes remission.

Main Results:

Significant heterogeneity exists in reported T2D remission rates following metabolic surgery.
Different bariatric procedures demonstrate varying efficacy in achieving diabetes remission.
The definition of diabetes remission significantly impacts reported success rates.

Conclusions:

Metabolic surgery offers a viable treatment option for T2D, but standardization of remission criteria is crucial.
Further research is needed to establish clear guidelines for metabolic surgery indications, especially for non-morbidly obese T2D patients.
Personalized approaches considering procedure type and remission criteria are essential for optimizing outcomes.