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[Three cases of liver abscess associated with the Streptococcus anginosus group]

Ryuta Shigefuku1, Michihiro Suzuki, Minoru Kobayashi

  • 1Division of Gastroenterology and Hepatology, St. Marianna University School of Medicine, Japan. r2shigefuku@marianna-u.ac.jp

Insights

Reports of pyogenic liver abscess (PLA) caused by the Streptococcus anginosus group (SAG) are increasing. SAG infections can lead to pylethrombophlebitis and often involve coinfection with anaerobic bacteria, complicating abscess formation.

Area of Science:

  • Microbiology
  • Hepatology
  • Infectious Diseases

Background:

  • Pyogenic liver abscess (PLA) is a serious intra-abdominal infection.
  • The Streptococcus anginosus group (SAG) is an increasingly recognized cause of PLA.
  • SAG infections are associated with specific complications like pylethrombophlebitis and polymicrobial infections.

Observation:

  • This report details 3 cases of PLA attributed to SAG.
  • One case presented with the complication of pylethrombophlebitis.
  • Two cases involved coinfection with anaerobic bacteria, highlighting synergistic abscess formation.

Findings:

  • The Streptococcus anginosus group (SAG) is a significant pathogen in pyogenic liver abscess (PLA) development.
  • Coinfection with anaerobic bacteria exacerbates PLA formation.
  • Pylethrombophlebitis is a notable complication of SAG-induced PLA.

Implications:

  • Increased awareness of SAG as a causative agent for PLA is crucial for timely diagnosis and treatment.
  • Understanding the role of anaerobic coinfection aids in predicting abscess severity and guiding therapy.
  • Recognizing the risk of pylethrombophlebitis in SAG PLA cases is essential for effective management and preventing further complications.

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