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Surgical infection in a videolaparoscopic cholecystectomy when using peracetic acid for the sterilization of
Edluza Maria Viana Bezerra de Melo1, Cristiano de Souza Leão, Luciana Marques Andreto
1Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Pernambuco, Brasil. edluzabmelo@hotmail.com
Objective:
To determine the frequency of surgical site infection in patients undergoing laparoscopic cholecystectomy with instruments sterilized by peracetic acid.
Methods:
We conducted a retrospective, cohort, descriptive, cross-sectional study. Peracetic acid has been used for sterilization following the protocol recommended by the manufacturer. We observed the criteria and indicators of process and structure for preventing surgical site infection pre and intraoperatively. For epidemiological surveillance, outpatient visits were scheduled for the 15th and between the 30th and 45th days after discharge.
Results:
Among the 247 patients, there were two cases of surgical site infection (0.8%). One patient was readmitted to systemic antibiotic therapy and percutaneous puncture; in the other the infection was superficial and followed at the clinic.
Conclusion:
Ethical issues prevent the conduction of a prospective study because of peracetic acid have been banned for the sterilization of instruments that penetrate organs and cavities. Nevertheless, these results encourage prospective case-control studies comparing its use (historical control) with ethylene oxide sterilization.
Insights
Surgical site infection (SSI) rates were evaluated in patients undergoing laparoscopic cholecystectomy using peracetic acid sterilization. The study found a low SSI frequency of 0.8%, suggesting peracetic acid may be a viable sterilization method.
Area of Science:
- Surgical Infection Prevention
- Sterilization Technologies
- Laparoscopic Surgery
Background:
- Surgical site infections (SSIs) are a significant concern in laparoscopic cholecystectomy.
- The choice of sterilization method for surgical instruments impacts infection rates.
- Peracetic acid is a chemical sterilant used for medical devices.
Purpose of the Study:
- To determine the frequency of surgical site infection (SSI) in patients undergoing laparoscopic cholecystectomy.
- To assess the efficacy of peracetic acid in sterilizing instruments for this procedure.
Main Methods:
- Retrospective, cohort, descriptive, cross-sectional study design.
- Observation of pre- and intraoperative SSI prevention criteria and indicators.
- Epidemiological surveillance through scheduled outpatient visits post-discharge.
Main Results:
- A total of 247 patients were included in the study.
- Two cases of surgical site infection (0.8%) were reported.
- Infections observed required antibiotic therapy or clinic follow-up.
Conclusions:
- The low SSI rate suggests peracetic acid sterilization may be effective for laparoscopic cholecystectomy instruments.
- Ethical considerations currently preclude prospective studies due to peracetic acid's ban for certain instrument types.
- Further case-control studies comparing peracetic acid with ethylene oxide sterilization are recommended.
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