Related Experiment Video
Updated: May 9, 2026

Protocol for Dengue Infections in Mosquitoes (A. aegypti) and Infection Phenotype Determination
Published on: July 4, 2007
[A mathematical model for controlling the spread of dengue]
Luis E López1, Aníbal Muñoz-Loaiza, Gerard Olivar-Tost
1Universidad Nacional de Colombia, Manizales, Colombia. lelopezm@unal.edu.co
Objective:
A mathematical model is presented in this paper showing the dynamics of dengue transmission. The goal was to studyAedes aegyptipopulation behaviour and that of affected people to scientifically support the decision-making involved in surveillance and control programmes.
Methods:
The proposed mathematical model involved eight differential equations having constant delays; each represented each population's variation either in humans or the mosquito vector.
Results:
Two of the mathematical model's simulation scenarios are presented; they were solved by means of an algorithm implemented in MATLAB software. The data was obtained from the Colombian Statistics Department (DANE), the World Health Organisation (WHO) and from a review of the pertinent literature. The data regarding human and vector populations was analysed (with and without using controls).
Conclusions:
The proposed mathematical model was able to simulate the dynamics of dengue transmission; it simulated the population-related behaviour ofAedes aegyptiand the affected people. This model could be a tool for scientifically supporting surveillance and control programmes' decision-making.

