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Updated: May 9, 2026

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Mouse Lumbar Vertebra Uniaxial Compression Testing with Embedding of the Loading Surface
Published on: December 1, 2023
Scores on the Safe Functional Motion test predict incident vertebral compression fracture
N J MacIntyre1, C P Recknor, S L Grant
1School of Rehabilitation Science, McMaster University, IAHS-403, 1400 Main St. West, Hamilton, ON, Canada, L8S 1C7, macint@mcmaster.ca.
Summary
The Safe Functional Motion (SFM) test predicts vertebral compression fractures (VCF). Higher SFM scores indicate better movement, significantly reducing the risk of future VCF by up to 27% over three years.
Area of Science:
- Gerontology
- Orthopedics
- Osteoporosis Research
Background:
- Functional movements can increase the risk of vertebral compression fractures (VCF).
- The Safe Functional Motion (SFM) test assesses physical function related to everyday activities.
- Hypothesis: SFM scores are associated with incident VCF.
Purpose of the Study:
- To determine if the Safe Functional Motion (SFM) test score predicts incident vertebral compression fractures (VCF).
- To evaluate the SFM test's utility in identifying individuals at risk for osteoporotic fractures.
Main Methods:
- A cohort of men and women aged 50+ with baseline SFM scores was analyzed.
- Data included demographics, bone mineral density, medication use, and VCF history.
- Multiple logistic regression adjusted for covariates to assess SFM's predictive value for incident VCF at 1 and 3 years.
Main Results:
- Baseline SFM score independently predicted incident VCF at 1-year (aOR=0.818) and 3-year (aOR=0.728) follow-ups.
- Each 10-point increase in SFM score decreased VCF odds by 18% (1 year) and 27% (3 years).
- Femoral neck bone mineral density and medication use were also significant predictors.
Conclusions:
- The Safe Functional Motion (SFM) test is a significant predictor of future vertebral compression fractures (VCF).
- SFM scores can help identify modifiable functional risk factors for VCF in older adults.
- The SFM test aids in risk stratification for osteoporotic fractures.
