Characterization of signalling pathways by reverse phase protein arrays

Katharina Malinowsky1, Claudia Wolff, Christina Schott

  • 1Department of Pathology, Technische Universität München, Munich, Germany.

Summary

This study presents a new method for extracting proteins from formalin-fixed, paraffin-embedded (FFPE) tissues for reverse phase protein array (RPPA) analysis. This technique helps understand ovarian cancer by analyzing epidermal growth factor receptor (EGFR) signaling and epithelial-mesenchymal transition (EMT) proteins.

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