Related Experiment Video
Updated: May 9, 2026

Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring
Published on: May 2, 2025
Heart Failure in Adults who had the Fontan Procedure: Natural History, Evaluation, and Management
Ari Cedars1, Susan Joseph, Philip Ludbrook
1, 660 S. Euclid Ave, Campus Box 8086, Saint Louis, MO, 63110, USA, acedars@dom.wustl.edu.
Insights
Fontan palliations create an artificial circulation, but patients often develop heart failure over time. This review covers the natural history, evaluation, and management of heart failure in Fontan circulation survivors.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Adult Congenital Heart Disease
Background:
- Fontan-type palliations are surgical procedures for single-ventricle physiology.
- These operations create a series circulation, altering normal pulmonary and systemic blood flow.
- The Fontan circulation, while life-sustaining, can lead to long-term complications.
Purpose of the Study:
- To review the current understanding of heart failure in patients with Fontan circulation.
- To summarize the natural history, evaluation, and management strategies for Fontan-associated heart failure.
- To increase awareness among cardiologists and adult congenital heart disease specialists regarding Fontan sequelae.
Main Methods:
- This is a review article.
- It synthesizes existing literature on Fontan circulation and heart failure.
- Data on natural history, evaluation, and management are summarized.
Main Results:
- Fontan circulation supports patients for decades.
- Progressive heart failure is a common long-term sequela.
- Specific data on Fontan heart failure are limited but growing.
Conclusions:
- Heart failure is an inevitable complication in many Fontan survivors.
- Familiarity with Fontan circulation's long-term effects is crucial for adult congenital heart disease specialists.
- Further research is needed to optimize management of heart failure in this population.
Opinion Statement:
Fontan type palliations are a group of operations employed in patients with only one functional ventricle. These procedures take the normally parallel pulmonary and systemic circulations and place them in series to reestablish separation between the two. The Fontan circulation established by such operations is a unique, artificial physiologic entity. Although the Fontan circulation supports patients for decades, patients eventually experience progressive heart failure. As this growing group of patients reaches adulthood, there is a need for general cardiologists as well as adult congenital heart disease specialists to be familiar with the long-term sequelae of the Fontan circulation. The purpose of the present review is to summarize the limited available data on heart failure of the Fontan, its natural history, evaluation, and management.
Related Concept Videos
Heart Failure V: Medical Management
Heart Failure VII: Nursing Interventions
Mitral Regurgitation IV: Nursing Management
Heart Failure IV: Classification and Diagnostic Evaluation
Mitral Stenosis IV: Nursing Management
Heart Failure II: Pathophysiology
