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Related Concept Videos

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents01:20

Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents

Diarrhea is characterized by the occurrence of frequent, watery bowel movements. Various factors can trigger diarrhea, including viral or bacterial infections, foodborne illnesses, side effects from certain medications, and underlying digestive disorders. If not adequately managed, diarrhea can lead to complications such as dehydration, electrolyte imbalances, and nutrient deficiencies. Severe diarrhea can lead to significant weight loss, malnutrition, and weakened immune function.
Adsorbents...
Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Cholera01:25

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents01:17

Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents

Diarrhea, a condition marked by frequent loose or watery bowel movements, can be triggered by multiple factors such as viral or bacterial infections, food intolerances, anxiety, medications, and digestive disorders. Symptoms may include abdominal pain, bloating, nausea, and cramping. Severe or prolonged diarrhea can lead to complications like electrolyte imbalances, malnutrition, and dehydration if left untreated.
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...

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Updated: May 9, 2026

Ginger Moxibustion, A Non-pharmacological Treatment, for Diarrhea in Patients with Chronic Obstructive Pulmonary Disease
03:25

Ginger Moxibustion, A Non-pharmacological Treatment, for Diarrhea in Patients with Chronic Obstructive Pulmonary Disease

Published on: December 27, 2024

[Travelers' diarrhea].

G D Burchard1, M Hentschke, T Weinke

  • 1Sektion Tropenmedizin, 1. Medizinische Klinik, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.

Deutsche Medizinische Wochenschrift (1946)
|August 6, 2013
PubMed
Summary
This summary is machine-generated.

Travelers diarrhea, often caused by bacteria like toxigenic Escherichia coli, impacts millions annually. Early self-treatment is recommended as prevention is limited.

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Microbiology

Context:

  • Travelers diarrhea affects millions of tourists globally each year.
  • Common causes include bacterial enteropathogens such as toxigenic Escherichia coli, Campylobacter, Shigella, Salmonella, Aeromonas, Plesiomonas, and non-cholera vibrios.
  • Viral pathogens like norovirus and parasitic pathogens such as Giardia lamblia also contribute to gastrointestinal illnesses in travelers.

Purpose:

  • To outline the common causes of travelers diarrhea.
  • To discuss potential treatment options including antibacterial therapies.
  • To emphasize the importance of early self-treatment due to limited prevention strategies.

Summary:

  • Bacterial enteropathogens are the primary cause of travelers diarrhea, necessitating awareness of potential treatments like ciprofloxacin, azithromycin, or rifaximin.
  • While viral infections are typically self-limiting, parasitic infections can lead to chronic gastrointestinal issues in returning travelers.
  • Given the limited effectiveness of prevention, travelers are advised to be informed about early self-treatment protocols for diarrhea.

Impact:

  • Informing travelers about the causes and self-treatment of diarrhea can mitigate the impact of this common travel-related illness.
  • Understanding the differential diagnosis between bacterial, viral, and parasitic causes is crucial for appropriate management.
  • This knowledge empowers travelers to manage their health effectively, reducing potential complications and improving travel experiences.