Sexually transmitted infections manifesting as proctitis

Chris A Lamb1, Elizabeth Iris Mary Lamb, John C Mansfield

  • 1Institute of Cellular Medicine , Newcastle University, Newcastle upon Tyne , UK ; Department of Gastroenterology , Newcastle upon Tyne Hospitals NHS Foundation Trust , Newcastle upon Tyne , UK.

Insights

Sexually transmitted infections (STIs) are increasing and can cause proctitis. This review distinguishes infectious causes from non-infective conditions, aiding diagnosis and management in gastroenterology.

Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Proctology

Background:

  • Rising incidence of sexually transmitted infections (STIs) presenting as proctitis.
  • Common causative organisms include Neisseria gonorrhoeae, Chlamydia trachomatis, herpes simplex virus, Treponema pallidum, Giardia lamblia, and Entamoeba histolytica.

Purpose of the Study:

  • To outline clinical discriminators for differentiating infectious proctitis from non-infective pathologies.
  • To guide key investigations for accurate diagnosis of STIs causing proctitis.
  • To provide management strategies and consultation advice for suspected STIs in gastroenterology.

Main Methods:

  • Review of clinical presentations and diagnostic criteria for various proctitis causes.
  • Comparison of infectious agents with non-infective conditions like inflammatory bowel disease, solitary rectal ulcer syndrome, and Behçet's syndrome.
  • Outline of recommended investigations and treatment protocols.

Main Results:

  • Identification of key clinical features that differentiate infectious proctitis.
  • Distinguishing STIs from non-infective causes such as inflammatory bowel disease.
  • Management strategies for various infectious etiologies are detailed.

Conclusions:

  • Accurate diagnosis of proctitis requires differentiating infectious STIs from non-infective conditions.
  • Effective management hinges on prompt and correct identification of causative organisms.
  • Enhanced gastroenterology consultation improves patient outcomes for suspected STIs.

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