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Updated: May 9, 2026
10:24
Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface
Published on: July 4, 2018
The human microbiota associated with overall health
Xiaofei Xu1, Zhujun Wang, Xuewu Zhang
1College of Light Industry and Food Sciences, South China University of Technology , Guangzhou , China and.
Critical Reviews in Biotechnology
|August 7, 2013
Summary
The human microbiota, comprising bacteria, eukaryotes, and viruses, significantly impacts health. Understanding its composition and influencing factors is key to future personalized health strategies.
Area of Science:
- Microbiology
- Human Health
- Genomics
Background:
- The human body hosts a complex ecosystem of microbes, including bacteria, eukaryotes, and viruses.
- Emerging evidence highlights the critical link between the human microbiota and overall health.
- Next-generation sequencing technologies enable detailed investigation of these microbial communities.
Purpose of the Study:
- To provide an overview of the relationship between human health and various microbiota (skin, nasal, throat, oral, vaginal, gut).
- To examine factors that modulate microbiota composition.
- To discuss future challenges and opportunities in manipulating microbiota for personalized health.
Main Methods:
- Literature review and synthesis of current research on human microbiota and health.
- Analysis of factors influencing microbiota composition, including host genetics and environmental exposures.
- Exploration of potential strategies for microbiota manipulation.
Main Results:
- The human microbiota plays a crucial role in maintaining health across various body sites.
- Host genetics and environmental factors significantly shape microbiota composition and dynamics.
- Targeting the microbiota holds promise for personalized health interventions.
Conclusions:
- The human microbiota is integral to health, with its composition influenced by multiple factors.
- Further research is needed to fully understand and harness the microbiota for therapeutic purposes.
- Personalized health strategies may increasingly involve modulation of the human microbiome.
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