Related Experiment Video
Updated: May 9, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
Common indications for pediatric antibiotic prophylaxis
1Pediatric Infectious Diseases and Tropical Pediatrics, Howard Hughes Medical Institute/Center for Vaccine Development, University of Maryland School of Medicine, 685 West Baltimore Street, Room 480, Baltimore, MD 21201, USA. mlaurens@medicine.umaryland.edu
Insights
Antimicrobial prophylaxis is vital for preventing infections in children, but requires careful physician prescribing in emergency and pediatric settings. This review covers key indications like exposures and wounds to guide appropriate antibiotic use.
Area of Science:
- Pediatrics
- Infectious Diseases
- Pharmacology
Background:
- Antimicrobial prophylaxis is standard for preventing infections in hospitals.
- Automated systems for prophylaxis are lacking in pediatric emergency and acute care settings.
- Physicians must ensure appropriate antibiotic prescribing for pediatric patients.
Purpose of the Study:
- To review common indications for antimicrobial prophylaxis in pediatric acute care.
- To guide physicians on the assessment, management, and disposition of pediatric patients for prophylaxis.
- To highlight the importance of appropriate antibiotic use in preventing pediatric infections.
Main Methods:
- Review of common pediatric acute care indications for antimicrobial prophylaxis.
- Analysis of assessment, management, and disposition strategies.
- Discussion of antibiotic prescribing practices.
Main Results:
- Identified key indications: traumatic wounds, meningococcal, pertussis, and influenza exposures.
- Emphasized physician responsibility in prescribing antibiotics.
- Highlighted the need for clear guidelines in pediatric settings.
Conclusions:
- Physician-led antibiotic prescribing is crucial for pediatric antimicrobial prophylaxis.
- Standardized approaches are needed for indications like exposures and wounds.
- Effective prophylaxis prevents infection and complications in pediatric patients.
Abstract:
Antimicrobial prophylaxis prevents infection and/or complications of infection, and is a routine practice for defined procedures in the hospital. Emergency rooms and pediatric acute care facilities do not have automated procedures for antimicrobial prophylaxis in place. The responsibility thus falls on the physician caring for the child to appropriately prescribe antibiotics to prevent infection and complications of infection. Common indications for antimicrobial prophylaxis in the pediatric acute care setting include traumatic wounds, meningococcal exposures, pertussis exposures, and influenza exposures. For each of these indications, the assessment, management and disposition of pediatric patients are reviewed.
Related Concept Videos
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Drug Dosing: Infants and Children
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Pharmacokinetics in Pediatric Patients: Drug Distribution
Acute Pyelonephritis II: Diagnostic Studies and Management