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Related Concept Videos

Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists01:18

Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists

Endothelins (ETs) are potent vasoactive peptides critical in the human body's various physiological and pathological processes. One of the most promising therapeutic strategies for treating pulmonary arterial hypertension (PAH) involves counteracting the effects of these endothelins using a class of drugs known as endothelin receptor antagonists.
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme (ECE). Of...

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Related Experiment Video

Updated: May 9, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

Pulmonary embolus in pregnancy.

Jennifer C Donnelly1, Mary E D'Alton

  • 1Department of OB/GYN, Columbia University Medical Center, 622 West 168th St, PH 12-32, New York, NY 10032, USA. jenniferdonnelly@mac.com

Seminars in Perinatology
|August 7, 2013
PubMed
Summary

Pulmonary embolism is a significant cause of maternal death. Low-molecular-weight heparin offers a safe and effective treatment for pregnant individuals experiencing this condition, balancing maternal health with minimal bleeding risks.

Keywords:
AntocoagulationLow molecular weight heparinVenous thromboembolism

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A Porcine Model of Acute Autologous Pulmonary Embolism
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Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Published on: January 26, 2024

Area of Science:

  • Obstetrics and Gynecology
  • Cardiovascular Medicine
  • Maternal Health

Background:

  • Venous thromboembolism (VTE) is a leading cause of pregnancy-related mortality in the US.
  • The risk of pulmonary embolism (PE) escalates during pregnancy, peaking postpartum.
  • VTE incidence is reported at 0.6-1.8 per 1000 deliveries.

Purpose of the Study:

  • To review the challenges in diagnosing and managing pulmonary embolism in pregnancy.
  • To highlight optimal treatment strategies for maternal outcomes and reduced hemorrhagic complications.

Main Methods:

  • Literature review on VTE in pregnancy.
  • Analysis of diagnostic and management strategies for pulmonary embolism.
  • Evaluation of treatment safety and efficacy.

Main Results:

  • Pulmonary embolism poses a significant risk throughout pregnancy and the postpartum period.
  • Effective management requires balancing maternal well-being against bleeding risks.
  • Low-molecular-weight heparin demonstrates safety and efficacy in treating pregnancy-related PE.

Conclusions:

  • Pulmonary embolism is a critical concern in maternal healthcare.
  • Low-molecular-weight heparin is a recommended treatment for pregnancy-related PE.
  • Optimizing patient outcomes necessitates careful management of VTE during pregnancy.