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Related Experiment Video

Updated: May 9, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Sickle cell crisis and pregnancy.

Marc R Parrish¹, John C Morrison

¹Department of OBGYN, University of Missouri Kansas City, St Luke's Hospital, 4401 Wornall, Kansas City, MO 64111, USA. marc7parrrish@hotmail.com

Seminars in Perinatology

|August 7, 2013

Summary

Pregnant women with sickle cell disease face increased risks during pregnancy and after birth. Close monitoring and specialized obstetric care are crucial for managing complications and ensuring maternal health.

Keywords:

Crisis Pregnancy Sickle cell disease

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Last Updated: May 9, 2026

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Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry

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Published on: November 5, 2019

Area of Science:

Obstetrics and Gynecology
Hematology
Maternal-Fetal Medicine

Background:

Sickle cell disease (SCD) is a genetic blood disorder that can affect pregnancy.
Pregnant individuals with SCD have historically faced higher rates of complications.

Purpose of the Study:

To summarize the risks and management considerations for pregnant women with sickle cell disease.
To emphasize the importance of specialized obstetric care for this population.

Main Methods:

Review of existing literature on sickle cell disease in pregnancy.
Analysis of complication rates and management strategies.

Main Results:

Pregnant women with SCD experience higher rates of antepartum, intrapartum, and postpartum complications compared to unaffected women.
Effective management requires a high index of suspicion and diagnostic skill.

Conclusions:

Access to high-risk obstetric care, patient education, and close follow-up are essential for minimizing maternal morbidity and mortality in pregnant women with SCD.
Optimal outcomes necessitate vigilant monitoring and prompt intervention for sickle cell crisis during pregnancy.