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Updated: May 9, 2026

Biochemical Measurement of Neonatal Hypoxia
Published on: August 24, 2011
[Severe neonatal acidosis: comparison and analysis of obstetrical practices in two French perinatal centers]
J Pommereau-Lathelize1, E Maisonneuve2, M Jousse1
1Service de gynécologie obstétrique, CHU de Poitiers, 2, rue de la Milétrie, 86000 Poitiers, France.
Objectives:
To identify and compare risk factors for severe neonatal acidosis, defined by an umbilical artery pH inferior to 7.00, and clinical practices in two different perinatal centers.
Patients And Methods:
In a retrospective study, from 2003 to 2008, in two university perinatal centers (Poitiers and Saint-Antoine in Paris) on all term pregnancies complicated by severe neonatal acidosis (umbilical artery pH<7.00), we elected to compare the following risk factors: maternal characteristics, medical and obstetrical histories, progress of pregnancy, labour and delivery as well as the neonatal status.
Results:
Among 23,508 births, 177 term newborns had severe neonatal acidosis. The rate was similar for both perinatal centers of Poitiers and Saint-Antoine (0.92% and 0.77% respectively). Factors associated with severe neonatal acidosis were similar in both centers: maternal age, thick meconium, prior cesarean section. There were differences in obstetrical practices between the two centers: there were more caesarean sections and assisted vaginal deliveries in Paris and more inductions of labour in Poitiers.
Conclusion:
Severe neonatal acidosis is associated with the geographical origin, the progress of labour and the mode of delivery. It seems that severe neonatal acidosis is unrelated to cesarean delivery.
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