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Updated: May 9, 2026
In Vitro Assay of Bacterial Adhesion onto Mammalian Epithelial Cells
Published on: May 16, 2011
Quantitative analysis of initial adhesion of bacterial vaginosis-associated anaerobes to ME-180 cells
António Machado1, Débora Salgueiro, Michael Harwich
1IBB - Institute for Biotechnology and Bioengineering, Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal; Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond, VA 23298-0678, USA.
Abstract:
Bacterial vaginosis is the leading vaginal disorder but the transition from health to this dysbiotic condition remains poorly characterized. Our goal was to quantify the ability of BV-associated anaerobes to adhere to epithelial cells in the presence of lactobacilli. Gardnerella vaginalis outcompeted Lactobacillus crispatus and Lactobacillus iners actually enhanced its adherence.
