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Updated: May 9, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
[Re-do coronary artery bypass grafting]
Yasutaka Yokoyama1, Kenji Kuwaki, Atsushi Amano
1Department of Cardiovascular Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Insights
Redo-coronary artery bypass grafting (redo-CABG) is a high-risk surgery. This paper reviews current indications, techniques, and outcomes for redo-CABG, aiming to improve patient safety and results.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
Context:
- Redo-coronary artery bypass grafting (redo-CABG) presents significant challenges compared to primary CABG.
- Increased technical difficulty and patient risk contribute to higher morbidity and mortality rates.
Purpose:
- To present current indications for redo-CABG.
- To outline safe surgical techniques and perioperative management strategies.
- To report contemporary outcomes of redo-CABG at the institution.
Summary:
- Annual reports show a decrease in redo-CABG procedures, possibly due to increased percutaneous coronary intervention (PCI) use.
- In-hospital mortality for redo-CABG remains significantly higher than for primary CABG.
- The paper details the approach to managing patients undergoing repeat cardiac bypass surgery.
Impact:
- Provides essential guidance for surgeons performing complex redo-CABG operations.
- Aims to optimize patient selection and surgical execution for better outcomes.
- Contributes to the understanding of current trends and results in redo-CABG surgery.
Abstract:
Redo-coronary artery bypass grafting( redo-CABG) still remains a challenging operation and is associated with a significantly higher risk of morbidity and mortality when compared with primary CABG. The higher risk of redo-CABG is largely attributable to the increased technical difficulty and the greater incremental risk in redo-CABG patients. Annual reports by the Japanese Association for Thoracic Surgery in recent years reveled that the absolute and relative number of redo-CABG gradually decreased, and in-hospital mortality did not change significantly over this periods and was much higher than primary CABG. The increasing use of percutaneous coronary intervention (PCI) for previous CABG patients could be a reason for the decrease of redo-CABG, and therefore surgery of redo-CABG is becoming more limited. This paper presents the current indications, safe surgical technique, and perioperative management of redo-CABG patients, as well as the contemporary results of redo-CABG in our institution.

