Related Experiment Video
Updated: May 9, 2026
Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
Published on: May 9, 2022
Multidisciplinary care in the intensive care unit for a patient with Prader-Willi syndrome: a dental approach
Insights
Prader-Willi syndrome (PWS) can cause severe oral health issues, including ulcerations linked to herpes. Early diagnosis and multidisciplinary care can significantly improve outcomes for PWS patients.
Area of Science:
- Genetics
- Neuroscience
- Pediatrics
Background:
- Prader-Willi syndrome (PWS) is a complex genetic disorder impacting development.
- PWS is associated with obesity, hypotonia, endocrine, and cognitive issues.
- Oral integrity can be compromised in individuals with PWS.
Purpose of the Study:
- To report a case of a 15-year-old male with PWS presenting with significant oral manifestations.
- To investigate the etiology of oral ulcerations in this PWS patient.
- To emphasize the importance of early diagnosis and intervention in managing PWS.
Main Methods:
- Clinical oral examination of a 15-year-old PWS patient.
- Assessment of oral hygiene, occlusion, and salivary characteristics.
- Excision biopsy of oral ulcerations for histopathological analysis.
Main Results:
- The patient exhibited bacterial plaque, gingivitis, poor occlusion, and viscous salivation.
- Multiple ulcerations were found on the lips, jugal mucosa, gums, and tongue.
- Biopsy revealed herpes-typical ulcerations, potentially linked to herpes encephalitis.
Conclusions:
- Oral ulcerations in PWS patients may be associated with herpes infections.
- Prompt diagnosis and early therapeutic interventions can mitigate PWS complications.
- Integrated, multidisciplinary care is crucial for effective PWS patient management.
Abstract:
Prader-Willi syndrome is a genetic neurobehavioral disease affecting children's development and resulting in obesity, reduced height, hypotonia, endocrine disorders and cognitive deficits, which may impair oral integrity. This study aims to report on a case involving a white male 15-year-old patient with Prader-Willi syndrome whose oral examination revealed bacterial plaque, gingivitis, poor occlusion, viscous salivation and multiple lip, jugal mucosa, inserted gum and tongue ulcerations. An excision biopsy revealed oral ulcerations typical of herpes, which were considered to be likely to correlate with herpes encephalitis. This result demonstrates that a large portion of the deleterious effects of Prader-Willi syndrome can be attenuated by appropriate diagnosis and early therapeutic intervention, highlighting the role of an integrated multidisciplinary team in the development of therapeutic protocols for Prader-Willi syndrome patients.
Related Concept Videos
01:28Acute Coronary Syndrome IV: Interprofessional Care
01:21Interdisciplinary Care: The Health Care Team-I
Physicians
The physician's primary responsibility is to diagnose illness and direct the medical or surgical treatment of the condition. The authority to admit patients to a healthcare agency or institution and practice care within that setting is granted to physicians by the healthcare agency or institution itself.
01:18Interdisciplinary Care: The Health Care Team-II
Physical Therapist
A physical therapist (PT) aims to restore function or prevent additional impairment in a patient following an injury or disease. Massage, heat, cold, water, sonar waves, exercises, and electrical stimulation are some treatments used by PTs to treat...
01:28Chronic Kidney Disease III: Interprofessional Care
01:29Chronic Pancreatitis II: Collaborative Care
Assessment:
01:27Peripheral Artery Disease III: Interprofessional Care