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19:15
Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Tender skin nodules in a newborn
Arijit Coondoo1, Raja Lahiry, Amlan Choudhury
1Department of Dermatology, KPC, Medical College and Hospital, Kolkata, India.
Indian Journal of Dermatology
|August 7, 2013
Summary
Subcutaneous fat necrosis of infancy is a rare newborn condition affecting adipose tissue, sometimes causing hypercalcemia. This disorder typically resolves completely and can explain inconsolable crying in infants.
Area of Science:
- Pediatrics
- Dermatology
- Neonatology
Background:
- Subcutaneous fat necrosis of infancy (SFNI) is a rare panniculitis affecting newborns.
- It involves the deposition of lipomucopolysaccharides in subcutaneous adipose tissue.
- SFNI can be associated with metabolic complications, notably hypercalcemia.
Purpose of the Study:
- To review the clinical presentation and management of subcutaneous fat necrosis of infancy.
- To highlight the association between SFNI and hypercalcemia.
- To inform pediatricians about this rare cause of neonatal distress.
Main Methods:
- Literature review of SFNI cases.
- Analysis of clinical features, complications, and outcomes.
- Case report synthesis focusing on diagnostic and therapeutic approaches.
Main Results:
- Complete resolution is the typical outcome for SFNI.
- Hypercalcemia is a significant, though not universal, complication.
- SFNI can manifest as a cause of persistent, inconsolable crying in newborns.
Conclusions:
- Subcutaneous fat necrosis of infancy is a benign condition with a favorable prognosis.
- Awareness of potential hypercalcemia is crucial for appropriate management.
- Pediatricians should consider SFNI in the differential diagnosis of neonatal inconsolable crying.
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