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Correlation between spirometry values and pulmonary artery pressure in young healthy subjects
Alon Grossman1, Michal Benderly, Alex Prokupetz
1Israeli Air Force Aero Medical Center, Tel Hashomer, Israel.
Respiratory Care
|August 8, 2013
Summary
Pulmonary artery systolic pressure (PASP) in young, healthy individuals shows no significant link to spirometry results. Lung function does not appear to influence PASP in this demographic.
Area of Science:
- Cardiology
- Pulmonology
- Physiology
Background:
- Pulmonary hypertension often co-occurs with lung disease.
- Investigating the relationship between pulmonary artery systolic pressure (PASP) and lung function in healthy young adults is crucial.
Purpose of the Study:
- To determine the association between spirometry values and PASP in young subjects without lung disease.
- To assess if lung mechanics influence PASP in a healthy, young population.
Main Methods:
- Analysis of resting spirometry and echocardiography data from Israeli Air Force applicants (1994-2010).
- Exclusion of subjects with overt lung disease.
- Statistical analysis of associations between PASP and various spirometry parameters (FVC, FEV1, FEV1/FVC, PEF, FEF50).
Main Results:
- 647 healthy young air force applicants (94% male, average age 18.16 years) were included.
- Mean PASP was 26.4 ± 5.2 mm Hg.
- No significant correlation was found between any spirometry values and PASP.
Conclusions:
- PASP in young, healthy individuals is not significantly associated with spirometry values.
- Lung mechanics do not appear to be a significant factor in determining PASP in this population.
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