Improved metabolite editing by the 1D soft COSY technique with 270 degrees Gaussian-shaped pulses

Recently we proposed Gaussian-shaped pulses to overcome the dynamic range problem within a 1D Soft COSY pulse sequence for the editing of metabolites in their natural environment. Similar to the development of the application of a COSY technique, the ECZOTIC sequence was introduced for the same purpose. A brief comparison of the abilities of both sequences is given in the first part of this communication, and the second part deals with the improvement of phase behavior within 1D Soft COSY by use of 270 degrees pulses.