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Association of possible osteopetrosis with acute myeloid leukaemia in a child
Rajniti Prasad1, B P Jaiswal, O P Mishra
1Department of Pediatrics, Institute of Medical Sciences, Varanasi, Uttar Pradesh, India.
Abstract:
Osteopetrosis is a rare disease characterised by an increase in bone mass, skeletal malformations and bone marrow failure due to defective bone resorption. We report a 3-month-old male child presented with chest infections, failure to thrive and hepatosplenomegaly and diagnosed with osteopetrosis associated with acute myeloid leukaemia M3 type (AML-M3). The patient died on day 7 of admission due to respiratory failure. To our knowledge, this is the first case where both osteopetrosis and AML is diagnosed in a patient.
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