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Updated: May 9, 2026

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
Published on: February 29, 2020
Correction of Chiari malformation due to closure of a concomitant thoracic meningocele
Jason A Chen1, Jorge A Lazareff
1Department of Neurosurgery, David Geffen School of Medicine at UCLA, 18-210 Semel, Box 957039, Los Angeles, CA, 90095-7039, USA, jasonchen@mednet.ucla.edu.
Introduction:
Chiari malformations are characterized by hindbrain herniation. Historically, some types have been linked to neural tube defects, but the causal relationship between the two conditions is still unclear.
Case Report:
We report on a full-term male neonate with a prenatally diagnosed posterior thoracic meningocele, whose MRI demonstrated Chiari malformation. The meningocele was closed in the second week of life. The Chiari-related symptoms rapidly improved following surgery. Postoperative MRI at 7 months of age showed ascent of the cerebellar tonsils to a normal position.
Discussion:
This case suggests that the traction on the cerebellum by a fixed spinal cord may play a role in the pathogenesis of the multifaceted Chiari malformations.
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