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Updated: May 9, 2026

Surgical Induction of Endolymphatic Hydrops by Obliteration of the Endolymphatic Duct
Published on: January 22, 2010
Endolymphatic hydrops revealed by magnetic resonance imaging in patients with acute low-tone sensorineural hearing
Mariko Shimono1, Masaaki Teranishi, Tadao Yoshida
1Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan. marikos@med.nagoya-u.ac.jp
Objective:
Acute low-tone sensorineural hearing loss (ALHL) has been reported to be associated with endolymphatic hydrops (EHs). However, evaluation of the size of the endolymphatic space has not been reported. We attempted to visualize EH in ALHL using magnetic resonance imaging (MRI).
Study Design:
Prospective diagnostic study.
Setting:
University hospital.
Methods:
We evaluated 25 ears of 25 unilateral ALHL patients. Three-tesla MRI was obtained 24 hours after intratympanic injection of gadolinium (Gd) (n = 5) or 4 hours after intravenous injection of Gd (n = 20). A radiologist blinded to the patients' clinical data classified the degree of EH in the vestibule and cochlea into 3 groups: none, mild, and significant.
Results:
On the affected sides, cochlear EH was recognized in 23 ears (92%) and was classified as significant EH (n = 15) or mild EH (n = 8); vestibular EH was detected in 22 ears (88%), classified as significant EH (n = 16) or mild EH (n = 6). Cochlear EH was more frequently observed in the affected ear than in the contralateral ear (90% versus 40%, p < 0.05).
Conclusion:
In ALHL, EH was observed not only in the cochlea but also in the vestibule as in Ménière's disease.
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