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The effect of Hexabrix tracheobronchography on the ultrastructure of the airway epithelium
1Research Institute for Child Development, Faculty of Pediatrics, University Hospital Motol, Prague, Czechoslovakia.
Pediatric Radiology
|January 1, 1990
Abstract:
The ultrastructure of the airway epithelium was studied after experimental Hexabrix tracheobronchography. Serious damage to the tracheal epithelium due to Hexabrix was recorded. 81 +/- 5% of goblet cells were stimulated to discharge mucus. 43 +/- 3% were completely exhausted and degenerated. The ciliated cells displayed vacuolar degeneration or severe pathological alteration. The average number of cilia/micron 2 fell to 3.3 +/- 0.5. As morphological signs of impaired self-cleaning ability the inspissated mucus and numerous bacteria appeared in the area of the disorganized ciliary border.