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Cardio-ankle vascular index relates to left ventricular ejection fraction in patients with heart failure. A

Chengmin Zhang1, Masahiro Ohira, Takuo Iizuka

  • 1Department of Cardiology, Zichuan District Hospital, Zibo, China.

International Heart Journal
|August 9, 2013
PubMed

Insights

The cardio-ankle vascular index (CAVI) may help assess afterload in heart failure patients. A decrease in CAVI correlated with improved left ventricular ejection fraction (LVEF) after treatment.

Area of Science:

  • Cardiovascular Medicine
  • Biomedical Engineering

Background:

  • Arterial stiffness, a predictor of heart failure progression, is closely linked to afterload.
  • The cardio-ankle vascular index (CAVI) is a noninvasive measure of arterial stiffness, independent of blood pressure.

Purpose of the Study:

  • To investigate the potential of CAVI as a marker of afterload in patients experiencing acute heart failure.
  • To explore the relationship between CAVI and left ventricular ejection fraction (LVEF) during heart failure treatment.

Main Methods:

  • Retrospective analysis of 30 acute heart failure patients.
  • Collected data included plasma brain natriuretic peptide (BNP) levels, CAVI, cardiothoracic ratio (CTR), and echocardiographic parameters during acute and chronic phases.
  • Patients were analyzed based on CAVI changes post-treatment.

Main Results:

  • Treatment led to significant increases in LVEF and significant decreases in CTR, BNP, and CAVI.
  • A significant negative correlation was found between changes in CAVI and LVEF.
  • CAVI improved significantly post-treatment only in patients with a notable decrease in CAVI.

Conclusions:

  • CAVI demonstrates an inverse correlation with LVEF following heart failure treatment.
  • CAVI may serve as a partial indicator of afterload in heart failure patients.
  • Further research is warranted to validate CAVI's role in managing heart failure.

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