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Updated: May 9, 2026

13:39
Optical Trapping of Nanoparticles
Published on: January 15, 2013
Selective fluorescent-free detection of biomolecules on nanobiochips by wavelength dependent-enhanced dark field
Seungah Lee1, Hyunung Yu, Seong Ho Kang
1Department of Applied Chemistry, Kyung Hee University, Yongin-si, Gyeonggi-do 446-701, Republic of Korea. shkang@khu.ac.kr.
Abstract:
Individual silver nanoparticle-conjugated target protein (cTnI) molecules on gold-nanopatterned chip were selectively detected by wavelength dependent-enhanced dark field illumination. Using specific nanoparticles with unique sizes and materials, the immunotargeted nanoparticle on the chips was detected at the single-molecule level by monitoring changes in the plasmonic resonance based on wavelength dependence.

