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Ocular allergy and keratoconus
Namrata Sharma1, Kavita Rao, Prafulla K Maharana
1Department of Cornea and Refractive Surgery, Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Indian Journal of Ophthalmology
|August 9, 2013
Summary
Ocular allergy may contribute to keratoconus development through eye rubbing and inflammation. Controlling allergies and eye rubbing is key to preventing this corneal ectasia.
Area of Science:
- Ophthalmology
- Corneal Diseases
- Immunology
Background:
- Keratoconus is the most common corneal ectatic disorder with largely unknown etiology.
- Ocular allergy is an implicated factor in keratoconus pathogenesis.
- Eye rubbing due to allergy can release inflammatory mediators, potentially altering corneal collagen.
Purpose of the Study:
- To explore the role of ocular allergy in keratoconus development and management.
- To highlight the association between allergy, eye rubbing, and corneal ectasia.
- To discuss the implications for early detection and treatment of keratoconus in allergic individuals.
Main Methods:
- Review of proposed pathogenesis linking ocular allergy to corneal changes.
- Analysis of clinical presentation and risk factors in keratoconus associated with allergy.
- Evaluation of surgical outcomes and complications in these specific cases.
Main Results:
- Allergy-associated keratoconus often presents earlier.
- Corneal topography can detect subtle forms.
- These cases have an increased risk of acute corneal hydrops and potential post-operative epithelial breakdown.
Conclusions:
- Controlling ocular allergy and associated eye rubbing is crucial for preventing corneal ectasias.
- Early detection via corneal topography is important for allergic individuals.
- While surgical outcomes are similar, careful post-operative care is needed for epithelial integrity.
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