Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Causes of Social Behavior III: Biological and Environmental Influences

Causes of Social Behavior III: Biological and Environmental Influences

Social behavior is a complex phenomenon that arises from the interaction between biological predispositions and environmental influences. This intricate interplay shapes how individuals think, feel, and act in various social contexts. Understanding these mechanisms requires insights from psychology, neuroscience, genetics, and evolutionary theory.Environmental Influences on Social BehaviorEnvironmental factors, including temperature, odors, and visual stimuli, play a crucial role in shaping...

Gene-Environment Interactions

Gene-Environment Interactions

Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...

Background and Environment Affect Phenotype

Background and Environment Affect Phenotype

Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...

Natural Selection and Adaptation

Natural Selection and Adaptation

Natural selection, a fundamental concept in evolutionary biology, is the mechanism by which evolution is driven, favoring organisms that are best adapted to their environments. This process enhances their chances of survival and reproduction. Adaptation, a key outcome of this process, involves genetic modifications that optimize an organism's functionality under specific environmental challenges, such as extreme cold or thinner air at high altitudes.
Beyond physical adaptations, psychological...

Behavioral Genetics and Its Designs

Behavioral Genetics and Its Designs

Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...

Impact of Social Context on Individuals

Impact of Social Context on Individuals

Social psychology examines how the real or imagined presence of others influences individuals' thoughts, feelings, and behaviors. A key concept in this field is the role of social context in shaping behavior. The same individual may act differently depending on the social setting, due to the varying expectations and norms associated with each environment. This context-dependent behavior illustrates the influence of social roles, which prescribe appropriate conduct in specific situations.Social...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Residential exposure to deadly gun violence and accelerated biological aging in a national sample of U.S. adolescents.

SSM - population health·2026

Same author

Corrigendum to "Cortisol stress reactivity and cumulative output associations with structural neural network architecture in adolescents" [Psychoneuroendocrinology 191 (2026) 107938].

Psychoneuroendocrinology·2026

Same author

Cortisol stress reactivity and cumulative output associations with structural neural network architecture in adolescents.

Psychoneuroendocrinology·2026

Same author

Authors Respond to "Racial and ethnic variation in socioeconomic differentials in young adult cardiovascular health".

American journal of epidemiology·2026

Same author

DNA Methylation Signatures of Atherosclerosis and Vascular-Related Outcomes in U.S. and Irish Population-Based Cohorts.

medRxiv : the preprint server for health sciences·2026

Same author

Differential Methylation by Early Life Adversity in the Future of Families Child Wellbeing Study.

bioRxiv : the preprint server for biology·2026

Search research articles

Related Experiment Video

Updated: May 9, 2026

Conditions Affecting Social Space in Drosophila melanogaster

Conditions Affecting Social Space in Drosophila melanogaster

Published on: November 5, 2015

Genetic differential sensitivity to social environments: implications for research.

Colter Mitchell¹, Sara McLanahan, Jeanne Brooks-Gunn

¹Colter Mitchell is with the Survey Research Center and Population Studies Center, University of Michigan, Ann Arbor, MI. Sara McLanahan is with the Department of Sociology and Woodrow Wilson School of Public and International Affairs, Princeton University, Princeton, NJ. Jeanne Brooks-Gunn is with the Teachers College and the College of Physicians and Surgeons, Columbia University, New York, NY. Irwin Garfinkel is with the School of Social Work, Columbia University. John Hobcraft is with the Department of Social Policy and Social Work, University of York, York, UK. Daniel Notterman is with the Department of Molecular Biology, Princeton University and Penn State College of Medicine, Pennsylvania State University, Hershey.

American Journal of Public Health

|August 10, 2013

Summary

The genetic differential sensitivity to social environmental (GDSE) model suggests some individuals are more affected by their environment due to genetics. Further research is needed to explore its health and public health implications.

More Related Videos

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes

Published on: December 15, 2023

Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease

Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease

Published on: January 7, 2014

Related Experiment Videos

Last Updated: May 9, 2026

Conditions Affecting Social Space in Drosophila melanogaster

Conditions Affecting Social Space in Drosophila melanogaster

Published on: November 5, 2015

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes

Published on: December 15, 2023

Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease

Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease

Published on: January 7, 2014

Area of Science:

Behavioral Genetics
Social Epidemiology
Developmental Psychology

Background:

The genetic differential sensitivity to social environmental (GDSE) model proposes that genetic predispositions influence individual responses to environmental factors.
Understanding gene-environment interactions is crucial for explaining health disparities and individual health trajectories.

Purpose of the Study:

To discuss key issues and considerations for applying the GDSE model in health research.
To highlight the need for theoretical advancements and methodological refinements in studying gene-environment interplay.

Main Methods:

Conceptual discussion and theoretical integration of existing research.
Exploration of potential measurement strategies for genetic sensitivity.
Examination of theoretical links to gene-environment correlations and life course perspectives.

Main Results:

Identified critical areas for GDSE model development: social environment conceptualization, multi-marker genetic assessment, and handling gene-environment correlations.
Highlighted the potential of the GDSE model for informing public health interventions and prevention strategies.
Emphasized the utility of integrating life course and developmental theories into GDSE research.

Conclusions:

The GDSE model offers a valuable framework for understanding how genetic factors modulate environmental influences on health.
Further theoretical and methodological advancements are necessary to fully leverage the GDSE model in health research and public health practice.
Integrating diverse theoretical perspectives will enhance the explanatory power and applicability of the GDSE model.