Related Experiment Video

Updated: May 9, 2026

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
06:46

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

Psycho-behavioral changes in children with type 1 diabetes mellitus

Xiao-Ping Zheng1, Shuo-Hui Chen

  • 1Department of Endocrinology, Children's Hospital, Zhejiang University School of Medicine and Key Laboratory of Reproductive Genetics, Zhejiang University, Ministry of Education, Hangzhou, China.

World Journal of Pediatrics : WJP
|August 10, 2013
PubMed

Insights

Children with type 1 diabetes mellitus (T1DM) show increased psycho-behavioral issues like anxiety and aggression. Poorly controlled T1DM is linked to more somatic complaints, highlighting the need for nursing interventions.

Area of Science:

  • Pediatrics
  • Child Psychology
  • Endocrinology

Background:

  • Type 1 diabetes mellitus (T1DM) is the most prevalent form of diabetes in pediatric populations.
  • Understanding the psycho-behavioral impact of T1DM in children is crucial for effective management and support.

Purpose of the Study:

  • To investigate psycho-behavioral changes in Chinese children diagnosed with T1DM.
  • To offer guidance for nurses and parents caring for children with T1DM.

Main Methods:

  • A cohort of 45 children with T1DM (mean age 10.40±3.01 years) was studied.
  • Patients were categorized into well-controlled and poorly-controlled groups based on HbA1c levels.
  • Achenbach's Child Behavior Checklist was used to assess psycho-behavioral changes, with 53 healthy children as a control group.

Main Results:

  • Children with T1DM exhibited significantly higher scores for withdrawal, anxiety/depression, attention problems, delinquent behavior, aggressive behavior, externalizing, and internalizing problems compared to controls.
  • The poorly-controlled T1DM subgroup showed significantly higher somatic complaints than the well-controlled group.
  • Both well-controlled and poorly-controlled T1DM subgroups displayed elevated scores in specific behavioral categories compared to healthy controls, with the poorly-controlled group showing a broader range of issues.

Conclusions:

  • Children diagnosed with T1DM are susceptible to developing psycho-behavioral problems.
  • Prompt and targeted nursing interventions are essential to address and mitigate these psycho-behavioral challenges in pediatric T1DM patients.
Abstract

More Related Videos

Psychophysiological Assessment of the Effectiveness of Emotion Regulation Strategies in Childhood08:09

Psychophysiological Assessment of the Effectiveness of Emotion Regulation Strategies in Childhood

Published on: February 11, 2017

Related Concept Videos

Type I Diabetes III: Clinical Manifestations01:19

Type I Diabetes III: Clinical Manifestations

Type 1 diabetes mellitus typically presents with rapid-onset symptoms due to the body’s inability to utilize glucose in the absence of insulin. Since insulin is required for glucose uptake into cells, its deficiency leads to hyperglycemia and cellular energy deprivation, resulting in characteristic clinical features.Polyuria and PolydipsiaOne of the earliest, most prominent symptoms is polyuria (excessive urination). When blood glucose concentrations rise above the renal threshold, the kidneys...
Type I Diabetes I: Introduction01:12

Type I Diabetes I: Introduction

Type 1 diabetes mellitus is a chronic metabolic disorder characterized by an absolute deficiency of insulin resulting from the autoimmune destruction of pancreatic β-cells. Although it can occur at any age, it is most commonly diagnosed in childhood, adolescence, or early adulthood. The loss of insulin production impairs cellular glucose uptake, resulting in persistent hyperglycemia and necessitating lifelong insulin therapy.Autoimmune Destruction of β-CellsThe hallmark of type 1 diabetes is an...
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type I Diabetes II: Pathophysiology01:26

Type I Diabetes II: Pathophysiology

Type 1 diabetes mellitus arises from an immune-mediated destruction of pancreatic β-cells, resulting in an absolute deficiency of insulin. This process develops in genetically susceptible individuals when autoimmunity, environmental exposures, and immunologic dysregulation converge to trigger a targeted attack on the insulin-producing cells of the pancreas. The β-cells are located within the islets of Langerhans and are essential for regulating blood glucose by facilitating cellular uptake of...
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Insulin: Dosing Regimen and Adverse Effects01:16

Insulin: Dosing Regimen and Adverse Effects

Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...