Effect of cyclic nucleotides and phosphodiesterase inhibition on morphine tolerance and physical dependence

Regulation of an opioid-binding protein in NG108-15 cells parallels regulation of delta-opioid receptors.

Proceedings of the National Academy of Sciences of the United States of America·1992

Antisense proenkephalin cDNA transfection decreases opioid binding in NG 108-15 cells.

Brain research. Molecular brain research·1992

Dual excitatory and inhibitory effects of opioids on intracellular calcium in neuroblastoma x glioma hybrid NG108-15 cells.

Molecular pharmacology·1992

Characterization of [3H]morphine binding to interleukin-1-activated thymocytes.

The Journal of pharmacology and experimental therapeutics·1992

Suppression by dynorphin A-(1-13) of the expression of opiate withdrawal and tolerance in mice.

European journal of pharmacology·1992

Opioid-binding cell adhesion molecule (OBCAM)-related clones from a rat brain cDNA library.

Gene·1992

Glycolysis-derived lactate contributes to H3K18la modification and CCL27 expression to promote placental angiogenesis.

Life sciences·2026

Mammary gland-specific deletion of MTA1 causes abrupt involution through activation of STAT3 signaling in lactating mice.

Life sciences·2026

Paraspeckles translate microbial insult-induced inflammation into neurovascular remodeling by enhancing CYR61-FGF2 signaling via RBM14 sequestration.

Life sciences·2026

Innate-adaptive immune crosstalk: TLR2 expression and CD8+ memory T cell responses in leprosy.

Life sciences·2026

A ketogenic enzyme HMGCS2 drives malignant progression in HER2-negative breast cancer via RAB23-mediated β-catenin/TCF signaling and mediates Apatinib resistance.

Life sciences·2026

Inhibition of SLC38A2 and loss of its N-glycosylation impair decidualization by promoting autophagy and apoptosis.

Life sciences·2026

Clinical Outcomes of a 3-day Benzodiazepine Detoxification Protocol With Continuous Subcutaneous Flumazenil Infusion: An Open-label Pilot Study.

Journal of addiction medicine·2026

Naloxone reversal of fentanyl-induced respiratory depression versus naloxone-induced precipitated withdrawal: an in silico utility model.

Frontiers in pharmacology·2026

Meta-Analysis: The Placebo Response in Modern Treatments for Cholestatic Pruritus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Alimentary pharmacology & therapeutics·2026

Blood-based biomarkers in Alzheimer's and Parkinson's disease: From molecular pathology to therapeutic potential.

International review of neurobiology·2026

Morphine for End-of-Life Dyspnea: Underuse in the Emergency Department Versus Inpatient Care.

Journal of pain and symptom management·2026

Adverse events during the diagnostic work-up for primary aldosteronism.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026

Related Experiment Videos

Effect of cyclic nucleotides and phosphodiesterase inhibition on morphine tolerance and physical dependence

Related Concept Videos

Regulation of an opioid-binding protein in NG108-15 cells parallels regulation of delta-opioid receptors.

Antisense proenkephalin cDNA transfection decreases opioid binding in NG 108-15 cells.

Dual excitatory and inhibitory effects of opioids on intracellular calcium in neuroblastoma x glioma hybrid NG108-15 cells.

Characterization of [3H]morphine binding to interleukin-1-activated thymocytes.

Suppression by dynorphin A-(1-13) of the expression of opiate withdrawal and tolerance in mice.

Opioid-binding cell adhesion molecule (OBCAM)-related clones from a rat brain cDNA library.

Glycolysis-derived lactate contributes to H3K18la modification and CCL27 expression to promote placental angiogenesis.

Mammary gland-specific deletion of MTA1 causes abrupt involution through activation of STAT3 signaling in lactating mice.

Paraspeckles translate microbial insult-induced inflammation into neurovascular remodeling by enhancing CYR61-FGF2 signaling via RBM14 sequestration.

Innate-adaptive immune crosstalk: TLR2 expression and CD8+ memory T cell responses in leprosy.

A ketogenic enzyme HMGCS2 drives malignant progression in HER2-negative breast cancer via RAB23-mediated β-catenin/TCF signaling and mediates Apatinib resistance.

Inhibition of SLC38A2 and loss of its N-glycosylation impair decidualization by promoting autophagy and apoptosis.

Clinical Outcomes of a 3-day Benzodiazepine Detoxification Protocol With Continuous Subcutaneous Flumazenil Infusion: An Open-label Pilot Study.

Naloxone reversal of fentanyl-induced respiratory depression versus naloxone-induced precipitated withdrawal: an in silico utility model.

Meta-Analysis: The Placebo Response in Modern Treatments for Cholestatic Pruritus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Blood-based biomarkers in Alzheimer's and Parkinson's disease: From molecular pathology to therapeutic potential.

Morphine for End-of-Life Dyspnea: Underuse in the Emergency Department Versus Inpatient Care.

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Effect of cyclic nucleotides and phosphodiesterase inhibition on morphine tolerance and physical dependence

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