Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

Mesenchymal Stem Cells

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...

iPS Cell Differentiation

iPS Cell Differentiation

The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.

Bone Marrow Sampling and Transplants

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dental Traumatology in Contemporary Practice: From Evidence to Education and Clinical Practice.

Dental traumatology : official publication of International Association for Dental Traumatology·2026

Same author

Perceptions and experiences of direct-to-consumer orthodontics: insights from a Reddit-based analysis.

Quintessence international (Berlin, Germany : 1985)·2026

Same author

Determinants of Dental Trauma Prevention and Management: Integrating Intimate Partner Violence, Caregiver Awareness, and Quality of Care.

Dental traumatology : official publication of International Association for Dental Traumatology·2026

Same author

The Modern Landscape of Dental Traumatology: From Clinical Precision to Social Responsibility.

Dental traumatology : official publication of International Association for Dental Traumatology·2026

Same author

Evaluating Guideline Adherence in Gemini-Powered Dental Trauma Workflows: Standalone Gemini Chat vs. Document-Grounded NotebookLM.

Dental traumatology : official publication of International Association for Dental Traumatology·2026

Same author

Comfort and Usability of Digital Versus Conventional Custom-Fit Mouthguards: A Randomized Clinical Trial.

Dental traumatology : official publication of International Association for Dental Traumatology·2026

Search research articles

Related Experiment Video

Updated: May 9, 2026

Integrated Bone Formation Through In Vivo Endochondral Ossification Using Mesenchymal Stem Cells

Integrated Bone Formation Through In Vivo Endochondral Ossification Using Mesenchymal Stem Cells

Published on: July 14, 2023

Stem cell therapy for bone regeneration: present and future strategies.

Hadar Zigdon¹, Liran Levin

¹Department of Periodontology, School of Graduate Dentistry, Laboratory of Bone Repair, Rambam Health Care Campus, Hailfa, Israel. hadar@technion.ac.il

The Alpha Omegan

|August 13, 2013

Summary

Severe alveolar bone loss can be treated with stem cell therapy. Mesenchymal stem cells (MSC) and endothelial progenitor cells (EPC) offer new possibilities for bone regeneration in dental implant surgery.

More Related Videos

Use of Human Perivascular Stem Cells for Bone Regeneration

Use of Human Perivascular Stem Cells for Bone Regeneration

Published on: May 25, 2012

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

Related Experiment Videos

Last Updated: May 9, 2026

Integrated Bone Formation Through In Vivo Endochondral Ossification Using Mesenchymal Stem Cells

Integrated Bone Formation Through In Vivo Endochondral Ossification Using Mesenchymal Stem Cells

Published on: July 14, 2023

Use of Human Perivascular Stem Cells for Bone Regeneration

Use of Human Perivascular Stem Cells for Bone Regeneration

Published on: May 25, 2012

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

Area of Science:

Regenerative medicine
Oral and maxillofacial surgery
Periodontology

Background:

Alveolar bone atrophy, caused by trauma, malignancy, or periodontal disease, necessitates bone restoration for patient function, phonetics, and aesthetics.
Current vertical bone augmentation techniques for dental implant placement are limited, especially in severe atrophic cases.

Purpose of the Study:

To explore the potential of mesenchymal stem cells (MSC) and endothelial progenitor cells (EPC) in enhancing bone regeneration.
To discuss current and future concepts of stem/progenitor cell-based regenerative therapy for severe alveolar bone defects.

Main Methods:

Review of current literature on stem cell applications in bone regeneration.
Discussion of the use of MSC and EPC in preclinical and clinical settings for alveolar bone augmentation.

Main Results:

Stem/progenitor cell-based therapies show promise for significant bone regeneration in atrophic conditions.
MSC and EPC possess properties that can enhance osteogenesis and vascularization, crucial for bone repair.

Conclusions:

Stem/progenitor cell-based regenerative therapy represents a promising approach for personalized treatment in periodontal, maxillofacial, and implant surgery.
This approach may overcome limitations of current methods, offering new therapeutic horizons for severe alveolar bone loss.