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Determination of diphenhydramine hydrochloride by flow injection with bromophenol blue and turbidimetric measurement
J Martinez Calatayud1, A Sanchez Sampedro, S Navasquillo Sarrion
1Departamento de Quimica Analitica, Facultad de CC Quimicas, Universidad de Valencia, Spain.
The Analyst
|June 1, 1990
Abstract:
The study of a number of diphenhydramine-dye systems was carried out in order to determine the most suitable precipitate for the turbidimetric determination of diphenhydramine using flow injection (FI). The reagent selected was Bromophenol Blue. The chemical and FI variables were optimised. The calibration graph was linear over the concentration range 50-230 p.p.m. of diphenhydramine hydrochloride. A number of interfering substances were also investigated.